The recreational drug of choice in hunter-gatherer communities is usually some form of hallucinogen. Hallucinogenic compounds are rarely addictive because they typically don’t operate on the dopamine-based reward circuits of the brain. By stark contrast, the drug of choice for agriculturalists is invariably an addictive agent that directly targets the reward circuits: almost always a pain-reducing soporific such as alcohol or opium, but occasionally a behavior-increasing dopaminergic substance such as cocaine or amphetamine.
Two things here:
First, why is it hunter-gatherers tend to prefer perception-expanding agents over feel-good chemicals?
Second, what is it about a domestication-based lifestyle that lends itself to drugs that target the brain’s reward circuits? And why is it that the drug of choice for agriculturalists is usually an experience-blunting analgesic agent?